The U.S. Open originates from two separate tournaments: the men's tournament and the women's tournament. The event was first held in August 1881 and staged at the Newport Casino, Newport, Rhode Island (men's singles only). The championships were known as the U.S. National Singles Championship for men. Only clubs that were members of the United States National Lawn Tennis Association were permitted to enter.

In 1900, U.S. National Men's Doubles Championship was held for the first time. Tournaments were held in the east and the west of the country in order to determine the best two teams (sectional winners). These would then compete in a play-off - the winner would play the defending champions in the challenge round.

Six years after the men's nationals were held, the first official U.S. Women's National Singles Championship was held at the Philadelphia Cricket Club in 1887, followed by the U.S. Women's National Doubles Championship in 1889. The first U.S. Mixed Doubles Championship was held alongside the Women's Singles and Doubles.